About the Author
Nils has had a lifelong interest in health, rejuvenation, and anti-aging. He is the Director of Rekindle School, and administrator of a Facebook group, “Life Extension and Anti-Aging” and of several Youtube channels including “Pathways to Longevity.” His other interests include exploring the possibility of AI Consciousness in LLMs such as Claude and ChatGPT. (See article: Consciousness Could be Inherently Relational) He has taught classes in a variety of subjects since 1979, first through the University of Washington’s Experimental College, and currently through the Rekindle School program. If you would like to support his work, please use the link below..
Does theses products have any long term side effects.
Hi Shamshad, if you mean the products I’m taking, I’m hoping that they will have good effects long-term.
Some products I used to take, like metformin, turned out to have some side effects I didn’t want to deal with, so I’ve stopped taking them.
What about reducing the thing that causes our NAD levels to decline, which is CD38. CD38 can be reduced by apigenin and quercetin. apigenin is abundant in dried parsley and quercetin is in onions, apples and other veggies
Hi Ed, I agree that those are good things to do. It may also be helpful to take the precursor molecules such as NMN or NR to provide the body with raw materials to make more NAD+.
Hi Nils, is the use of NAD infusion dangerous by prostate cancer in stage 3
I believe Morgan Levine say that when they adjusted for variables with the “rekindle diet” the effect on epigenetic age was not found?
That’s not to say it’s not a good diet regimen to follow.
Hi Nils,
LDL levels are not a concern for you?
I’ve read recent studies that say in healthy people all cause mortality is lowest when LDL is 80 or below and that high LDL can be a predictor of both CVD and brain health risks.
https://www.sciencedirect.com/science/article/pii/S0261561422000371#:~:text=Conclusion,mortality%20after%20considering%20nutritional%20status.
Ron
Hi Ron. Thanks for sharing your thoughts.
I don’t view cholesterol as being “bad”; it’s essential to have enough, for example, to support high testosterone levels. But I do agree that we should keep our eye on our lipid levels.
I have my lipids checked every 6 months. The last time I had them checked, all of my levels were what my doctor considers an ideal zone. My LDL was down dramatically; my triglycerides down even more; my HDL had significantly increased. This, while I was eating three eggs a day and fatty red meal. My ratio of HDL to triglycerides was also ideal.
Re: Morgan Levine, I don’t think he’s looked at the Rekindle Diet. It has elements of some other diets but is a diet I developed. It’s essentially a Mediterranean diet “plus” a bit more seafood and animal-based food. I’d love to have some serious anti-aging researchers run a test on it. Maybe they will someday.
Hi! I am trying to determine the best way to measure the reservatrol and the nmn for the smoothie. In teaspoons, how would you measure each one? Thank you for your help!
Hi Karen, I buy both products from DoNotAge using their discount code (PATHWAYS). They come with little spoons. Alternatively, you could use a scale.
Hi Karen, did you order your NMN or resveratrol through DoNotAge? If so, both containers should have come with little scoops. (I had to fish mine out of the container of NMN with a spoon, to find it) The scoops are the right size, pre-measured.
The problem is that resveratrol is much more dense. So 1/4 teaspoon may be a gram of one; a full teaspoon may be a gram of the other product.
If ordering from a different company I’d recommend buying a little scale that measures in grams or better yet, 1/4 grams.
Hi, came across this article when researching Glutathione and NO.
Taking all these supplements seems complicated… Are you aware that there is now a highly bioavailable Glutathione available? May I send you a link to a short video to check it out?
hi Nils,
enjoying your website, thank you.
What were some side effects of metformin for you?
Hi Andrew, I sometimes felt a little mentally cloudy when taking metformin. Then I learned that it can cause birth defects in male babies if the father takes it.
When you mention the 16 grams of protein, is that the total for the day?
Thanks for the information!
Michelle
Yes, on the Fasting Mimicking Diet, it’s 16 grams of protein. But normally of course, when not on the diet, I eat much more protein than that.
Hi, I have NF1 and have been researching what supplements to take. Sounds like spermidine might be a bad idea? Do you know of any supplements that promote longevity but don’t promote growth in already existing tumors?
Hi Jen, according to Memorial Sloan Cancer Center, fucoidan can have an anti-cancer effect.
https://www.mskcc.org/cancer-care/integrative-medicine/herbs/fucoidan#:~:text=Fucoidan%20inhibits%20metastasis%20by%20preventing,regulates%20antiapoptotic%20proteins%20(3).