Sea Buckthorn Berry Powder Activates AMPK, is Anti-Cancer, lowers LDL and Triglycerides, and Increases Stem Cells in the Body

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by Nils Osmar. Updated Feb. 29, 2024

First, a caveat: Sea Buckthorn is not the same as Buckthorn! They’re completely different plants which have similar names. Buckthorn can be toxic; sea buckthorn, when used thoughtfully, shows evidence of being highly beneficial, particularly for people interested in healthy life extension.

Health benefits

I’ve been taking sea buckthorn powder, and also sometimes taking an oil made from it for the past three years. I take them because:

When to take Sea Buckthorn

In my opinion, it’s good to take sea buckthorn during periods when we’re trying to activate AMPK (not mTOR). (AMPK is regarded as a longevity pathway, and when activated is associated with the extension of healthy lifespan in lab animals; mTOR is a growth pathway, supporting muscle protein synthesis and helping to prevent sarcopenia as we age. Some activation of AMPK (and breaks from mTOR activation) are important if our goal is extreme longevity.

What I’ve been doing in recent months is starting my days with a cup of decaf coffee (made caffeine-free through a water-extraction process, not the addition of chemicals). I usually add some sea buckthorn berry powder to my morning coffee. I’ll sometimes add it to the grounds while the coffee is brewing; other times I’ll stir some in after pouring the coffee into a mug. It adds a bitter, tangy taste that’s reminiscent to me of grapefruit peels. (The taste is not for everyone! I like it, but I suspect most people might prefer their coffee without it. In that case, one might just mix some in a little cup of water and gulp it down, then have some coffee.) I also take many other supplements, but I consider sea buckthorn to be a key part of my protocol.

“Free Stem Cell Therapy

When we fast or do fasting mimicking diets of three days or more, the body cannibalizes senescent cells for fuel. At the end of the fast, our bone marrow creates a flood of new stem cells which travel around the body replacing the cannibalized cells. (Dr. Valter Longo verified this a few years ago in his studies at Stanford University.) Some view this as “free stem cell therapy.”

Sea buckthorn berry oil both supports the mobilization of some types of stem cells, and increases the number of circulating stem cells. This occurs whether or not we’re fasting.

Sea buckthorn berry oil contains several types of fatty acids, including small amounts of palmitoleic acid, vaccenic acid, oleic acid, omega-3, linoleic acid, linolenic acid, stearic acid and palmitic acid.Note: One side effect is that it thins the blood, so caution should be taken if you’re on blood thinners. Again, in my own case, I’ve stopped taking the oil and am taking a powder.

From one (human) study:

“By documenting the ability of SBB-PE to support stem cell mobilization and to increase the number of circulating stem cells, we have uncovered a new mechanism of action behind many of the health benefits that have been historically associated with SBB, as a part of its use in Tibetan, Mongolian, and Chinese traditional medicine.”

“Once mobilized, bone marrow stem cells can participate in the process of tissue repair and modulate local inflammation, supporting the use of SBB-PE in overall health maintenance.””

Conclusion: Consumption of SBB-PE resulted in selective mobilization of stem cell types involved in regenerative and reparative functions.”

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  1. Mike Grant says:

    Hello, please explain what SBB-PE means, is this shorthand for a specific extract of the berry? Thanks.

  2. Hi Mike, SFF-PE is an extract of sea buckthorn berries.

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