by Nils Osmar. January 27, 2022
NMN is one of those supplements I don’t always expect a big jolt from. But at times I get one.
When I first started taking it, I was using tiny doses and didn’t feel anything. I increased the dose, and I did feel more alert… sometimes hyper-alert actually, till I got used to it. But that effect eventually wore off as time went by.
These days, even when I take large doses, I don’t always feel an impact. I’m sure it’s still affecting me, but my body’s accustomed to it. But if I take the ingredients below all together, I’ll feel a startling effect.
- Ora Organic Green Powder (1 or 2 scoops)
- DoNotAge NMN powder (to boost NAD) (2 grams)
- DoNotAge Resveratrol powder (to activate SIRT1) (0.5 to 1 grams)
- Gaia Herbs Black elderberry syrup (to activate SIRT6) (1 teaspoon)
- Lekithos liquid lecithin (2 teaspoons) or MicroIngredients Sunflower Lecithin (2-3 teaspoons)
- DoNotAge TMG (2 capsules)
- DoNotAge SIRT6 Activator (3 capsules)
- Optional: Fisetin and Quercetin (500 mg each)
- I add the elderberry extract to a glass of water or celery juice, add the green powder, add the NMN and resveratrol and lecithin, then blend it for three minutes on high.
- I sometimes add a dash of olive oil or avocado oil for the Oleic acid, which activates SIRT1 and SIRT6.
- I then blend them for 3 minutes on high to simulate the way liposomal vitamins are made. (I know that some people use a more complex method which involves an ultrasonic cleaner, but I find that blending alone works fine, as long as I blend for long enough.) (I’ll sometimes use a high speed mixer instead.)
- I take the other supplements in tablet form with the celery/NMN/resveratrol/lecithin drink.
- The effect is startling actually. Colors look brighter, and everything looks more vivid and three dimensional somehow. If anything, I feel overstimulated. My mind sometimes starts racing. This effect lasts for about 30 minutes.
- The “activator” which makes a difference seems to be the lecithin. This makes sense, because lecithin is rich in phosphatidylcholine, which the body uses to make acetylcholine, a neurotransmitter.
- When I originally tried this combination, I thought my response might be to the lecithin due to the choline. But I don’t get anything in any way similar when taking lecithin alone.
- I posted a version of this information about a year ago in the Facebook Life Extension and Anti-Aging Group. A group member raised an interesting question, which is whether we should expect to “feel anything” when we’re taking NAD boosters.
- Some people do; some don’t. A lot of people don’t feel anything. So I’m not saying that “feeling energized” is the only reason for taking them. But I have known people who drifted away from taking them because they had no idea if they were doing anything.
- Taking them with a little lecithin, to me, makes the effects more apparent…. like making something which had been invisible, suddenly visible to the eye.
- But even if we don’t take the lecithin or don’t feel much of a tangible response, it seems likely that we may be getting a good long-term effect from taking NAD boosters.